My individual research project focuses on optimizing methods for 3D bioprinting of in-vitro models, with a keen eye on critical factors like base plate temperature, extrusion head temperature, printing pressure, velocity, and ultraviolet light contact.

In the lab, I navigate the complexities of GelMA efficacy using the Instron 5943 machine, employing mass swelling testing to unveil hydrogel physical properties. Proficient in cell culture, I actively cultivate a conducive environment for 12z and iEc-ESC (stromal) cells, essential components for my 3D printing endeavors.

This cutting-edge research aims to contribute to the identification of dysregulated genes, offering not only diagnostic tools but also potential therapeutic targets for individuals grappling with the painful realities of Endometriosis. Understanding the nuanced layers of the endometrium, from the stratum basalis to the stratum functionalis, provides a crucial foundation for developing physiological models that mimic the intricate cell-matrix interactions within the female reproductive system.

Endometriosis affects 10% of individuals with female reproductive systems, causing a myriad of health issues, from fertility problems to inflammation. Current diagnostic delays and limited treatment options underscore the urgency of my work. By challenging the status quo of 2D models and bridging the gap between mice models and human physiology, my research seeks to unravel the complexities of Endometriosis, offering hope to those facing financial strain, infertility, and severe pain. Together, we aim to transform limited understandings into comprehensive pathophysiological knowledge for effective treatment.